Endocrine Abstracts

Clinical Case: A 51 year old woman of south Asian descent was referred by her GP to outpatient endocrine clinic for assistance with her mixed hyperlipidaemia (Cholesterol 9.5 mmol/L, HDL Cholesterol 1.03 mmol/L Triglycerides 6.7 mmol/L). Her past medical history included a previous hemithyroidectomy for removal of a thyroid nodule (histologically benign) and obesity.The patient’s symptoms were of weight gain (5 kg in 18 months...

Clinical Case: A 51 year old woman of south Asian descent was referred by her GP to outpatient endocrine clinic for assistance with her mixed hyperlipidaemia (Cholesterol 9.5 mmol/L, HDL Cholesterol 1.03 mmol/L Triglycerides 6.7 mmol/L). Her past medical history included a previous hemithyroidectomy for removal of a thyroid nodule (histologically benign) and obesity.The patient’s symptoms were of weight gain (5 kg in 18 months...

You don’t have to be a digital native to use technology effectively in teaching. Even self-confessed technophobes can make meaningful improvements in their use of digital learning with only a little bit of guidance and support. Technology is a ubiquitous feature of higher education, which has been consolidated during the COVID-19 pandemic. However, with so many options on the market it can be incapacitating to try and choose. This is further complicated by local institut...

Case History: A 26 year old female underwent Roux-en-Y gastric bypass (RYGB) surgery for intractable peptic ulcer disease on a background of obesity. She had a history of 40kg weight gain over 8 years (weight 123 kg, BMI 41.1 kg/m2), hypertension, depression, insomnia and newly diagnosed type 2 diabetes. Following surgery, weight loss was disappointing (nadir 112 kg, −11 kg, −8.9%TBW, −22.9%EBW, BMI 37.5 kg/m2) and diabetes and hypertens...

Lawyers need doctors. When the work of the legal profession leads into areas of clinical medicine it is important that expert clinicians are there to explain and advise on the clinical issues. A good clinician can give valuable advice to the parties involved, and can also assist the courts in reaching a just and equitable conclusion.In endocrinology an expert is most commonly asked to advise in matters relating to an allegation of clinical negligence. So...

Lawyers need doctors. When the work of the legal profession leads into areas of clinical medicine it is important that expert clinicians are there to explain and advise on the clinical issues. A good clinician can give valuable advice to the parties involved, and can also assist the courts in reaching a just and equitable conclusion.In endocrinology an expert is most commonly asked to advise in matters relating to an allegation of clinical negligence. So...

The use of RAI for remnant ablation, as adjuvant therapy or as treatment for recurrent or metastatic disease is undergoing a significant reappraisal, based on its questionable efficacy in various disease contexts. Until recently postoperative RAI treatment was given to all patients with thyroid cancer regardless of the pathological stage of the disease. Although its use for low risk forms of thyroid cancer has diminished, current indications for adjuvant RAI treatment are not ...

To date, all major guidelines designate LT4 as the standard. Are symptoms a reliable indicator of the presence of hypothyroidism? Fatigue in primary care, predicts a lifetime diagnosis of depression or anxiety more frequently than other outcomes. Tiredness has been examined in 26 meta-analyses. Only 4.3% of tired subjects have identifiable somatic disease (includes anemia, diabetes and hypothyroidism). In studies with control groups, the prevalence of somatic diseases was iden...

Many patients taking medical therapy for a prolactinoma may assume that they need treatment for life. In reality it is often possible to stop treatment after a while.In considering whether to stop treatment of a prolactinoma, it is helpful first to review the diagnosis and clarify whether the patient has a prolactinoma. Hyperprolactinaemia has many causes, and some patients are treated without a secure diagnosis of prolactinoma.For...

The last decade has seen an explosion in scientific breakthroughs as technology drives new discoveries. It is an exciting time to be a scientist! So why are the numbers of young people studying science declining?To arrest this slide there are innumerable initiatives to encourage researchers to engage with young people directly. But, for all that it is exciting to be a scientist, are scientists exciting? Can social skills learnt by breeding zebrafish trul...